Journal of Manipulative and Physiological Therapeutics
Volume 30, Issue 2 , Pages 98-108 , February 2007

Magnetic Resonance Imaging Findings as Predictors of Clinical Outcome in Patients With Sciatica Receiving Active Conservative Treatment

  • Tue Secher Jensen, DC, MSc

      Affiliations

    • Chiropractor, The Back Research Center, Ringe, University of Southern Denmark, Odense, and Clinical Locomotion Science, Denmark
    • Corresponding Author InformationSubmit requests for reprints to: Tue Secher Jensen, DC, MSc, The Back Research Center, University of Southern Denmark, Backcenter Funen, Lindevej 5, DK-5750 Ringe, Denmark.
  • ,
  • Hanne B. Albert, PT, MPH, PhD

      Affiliations

    • Senior researcher, The Back Research Center, Ringe, University of Southern Denmark, Odense, and Clinical Locomotion Science, Denmark
  • ,
  • Joan S. Sorensen, MD

      Affiliations

    • Radiologist, The Back Research Center, Ringe, University of Southern Denmark, Odense, and Clinical Locomotion Science, Denmark
  • ,
  • Claus Manniche, MD, DrMedSci

      Affiliations

    • Head of Department, Backcenter Funen, Ringe and Professor, The Back Research Center, Ringe, University of Southern Denmark, Odense, and Clinical Locomotion Science, Denmark
  • ,
  • Charlotte Leboeuf-Yde, DC, MPH, PhD

      Affiliations

    • Research Professor, The Back Research Center, Ringe, University of Southern Denmark, Odense, and Clinical Locomotion Science, Denmark

Received 10 July 2006 ,Revised 17 August 2006 ,Accepted 24 August 2006.

References 

  1. Heliovaara M, Impivaara O, Sievers K, et al. Lumbar disc syndrome in Finland. J Epidemiol Community Health. 1987;41:251–258
  2. Han TS, Schouten JS, Lean ME, et al. The prevalence of low back pain and associations with body fatness, fat distribution and height. Int J Obes Relat Metab Disord. 1997;21:600–607
  3. Beattie PF, Meyers SP, Stratford P, et al. Associations between patient report of symptoms and anatomic impairment visible on lumbar magnetic resonance imaging. Spine. 2000;25:819–828
  4. Karppinen J, Malmivaara A, Tervonen O, et al. Severity of symptoms and signs in relation to magnetic resonance imaging findings among sciatic patients. Spine. 2001;26:E149–E154
  5. Porchet F, Wietlisbach V, Burnand B, et al. Relationship between severity of lumbar disc disease and disability scores in sciatica patients. Neurosurgery. 2002;50:1253–1259
  6. Carragee EJ, Kim DH. A prospective analysis of magnetic resonance imaging findings in patients with sciatica and lumbar disc herniation. Correlation of outcomes with disc fragment and canal morphology. Spine. 1997;22:1650–1660
  7. Takada E, Takahashi M, Shimada K. Natural history of lumbar disc hernia with radicular leg pain: Spontaneous MRI changes of the herniated mass and correlation with clinical outcome. J Orthop Surg (Hong Kong). 2001;9:1–7
  8. Komori H, Okawa A, Haro H, et al. Factors predicting the prognosis of lumbar radiculopathy due to disc herniation. J Orthop Sci. 2002;7:56–61
  9. Vroomen PC, Wilmink JT, de KM. Prognostic value of MRI findings in sciatica. Neuroradiology. 2002;44:59–63
  10. Komori H, Shinomiya K, Nakai O, et al. The natural history of herniated nucleus pulposus with radiculopathy. Spine. 1996;21:225–229
  11. Ahn SH, Park HW, Byun WM, et al. Comparison of clinical outcomes and natural morphologic changes between sequestered and large central extruded disc herniations. Yonsei Med J. 2002;43:283–290
  12. Yukawa Y, Kato F, Matsubara Y, et al. Serial magnetic resonance imaging follow-up study of lumbar disc herniation conservatively treated for average 30 months: relation between reduction of herniation and degeneration of disc. J Spinal Disord. 1996;9:251–256
  13. Fardon DF, Milette PC. Nomenclature and classification of lumbar disc pathology. Recommendations of the Combined Task Forces of the North American Spine Society, American Society of Spine Radiology, and American Society of Neuroradiology. Spine. 2001;26:E93–E113
  14. Bozzao A, Gallucci M, Masciocchi C, et al. Lumbar disk herniation: MR imaging assessment of natural history in patients treated without surgery. Radiology. 1992;185:135–141
  15. Bush K, Cowan N, Katz DE, et al. The natural history of sciatica associated with disc pathology. A prospective study with clinical and independent radiologic follow-up. Spine. 1992;17:1205–1212
  16. Kawaji Y, Uchiyama S, Yagi E. Three-dimensional evaluation of lumbar disc hernia and prediction of absorption by enhanced MRI. J Orthop Sci. 2001;6:498–502
  17. Matsubara Y, Kato F, Mimatsu K, et al. Serial changes on MRI in lumbar disc herniations treated conservatively. Neuroradiology. 1995;37:378–383
  18. Saal JA, Saal JS, Herzog RJ. The natural history of lumbar intervertebral disc extrusions treated nonoperatively. Spine. 1990;15:683–686
  19. Splendiani A, Puglielli E, De Amicis R, et al. Spontaneous resolution of lumbar disk herniation: predictive signs for prognostic evaluation. Neuroradiology. 2004;46:916–922
  20. Teplick JG, Haskin ME. Spontaneous regression of herniated nucleus pulposus. AJR Am J Roentgenol. 1985;145:371–375
  21. Jensen TS, Albert HB, Soerensen JS, et al. Natural course of disc morphology in patients with sciatica: an MRI study using a standardized qualitative classification system. Spine. 2006;31:1605–1612
  22. Albert HB. Conservative treatment of patients with severe sciatica—a randomized clinical controlled trial [in Danish]. Ph.D. Dissertation, Faculty of Health Sciences, University of Southern Denmark. Odense: University of Southern Denmark. 2004. p. 1-40.
  23. Albert HB, Jensen AM, Dahl D, et al. Criteria validation of the Roland Morris questionnaire. A Danish translation of the international scale for the assessment of functional level in patients with low back pain and sciatica. Ugeskr Laeger. 2003;165:1875–1880
  24. Manniche C, Asmussen K, Lauritsen B, et al. Low Back Pain Rating Scale: validation of a tool for assessment of low back pain. Pain. 1994;57:317–326
  25. Sorensen JS, Kjaer P, Jensen TS, et al. Low field magnetic resonance imaging of the lumbar spine: reliability of qualitative evaluation of disc and muscle parameters. Acta Radiol. 2006;47:947–953
  26. Kjaer P. Low back pain in relation to lumbar spine abnormalities as identified by magnetic resonance imaging. Ph.D. Dissertation, Faculty of Health Sciences, University of Southern Denmark. Odense: University of Southern Denmark. 2004.
  27. Modic MT, Obuchowski NA, Ross JS, et al. Acute low back pain and radiculopathy: MR imaging findings and their prognostic role and effect on outcome. Radiology. 2005;237:597–604
  28. Bejia I, Younes M, Zrour S, et al. Factors predicting outcomes of mechanical sciatica: a review of 1092 cases. Joint Bone Spine. 2004;71:567–571
  29. Kikuchi S, Konno S, Kayama S, et al. Increased resistance to acute compression injury in chronically compressed spinal nerve roots. An experimental study. Spine. 1996;21:2544–2550
  30. Olmarker K, Rydevik B, Holm S. Edema formation in spinal nerve roots induced by experimental, graded compression. An experimental study on the pig cauda equina with special reference to differences in effects between rapid and slow onset of compression. Spine. 1989;14:569–573
  31. Rydevik BL, Pedowitz RA, Hargens AR, et al. Effects of acute, graded compression on spinal nerve root function and structure. An experimental study of the pig cauda equina. Spine. 1991;16:487–493
  32. Ito T, Takano Y, Yuasa N. Types of lumbar herniated disc and clinical course. Spine. 2001;26:648–651
  33. Tubach F, Beaute J, Leclerc A. Natural history and prognostic indicators of sciatica. J Clin Epidemiol. 2004;57:174–179
  34. Beauvais C, Wybier M, Chazerain P, et al. Prognostic value of early computed tomography in radiculopathy due to lumbar intervertebral disk herniation. A prospective study. Joint Bone Spine. 2003;70:134–139
  35. Heliovaara M, Knekt P, Aromaa A. Incidence and risk factors of herniated lumbar intervertebral disc or sciatica leading to hospitalization. J Chronic Dis. 1987;40:251–258
  36. Kjaer P, Leboeuf-Yde C, Korsholm L, et al. Magnetic resonance imaging and low back pain in adults: a diagnostic imaging study of 40-year-old men and women. Spine. 2005;30:1173–1180
  37. Taylor BA, Casas-Ganem J, Vaccaro AR, et al. Differences in the work-up and treatment of conditions associated with low back pain by patient gender and ethnic background. Spine. 2005;30:359–364
  38. Arendt-Nielsen L, Bajaj P, Drewes AM. Visceral pain: gender differences in response to experimental and clinical pain. Eur J Pain. 2004;8:465–472
  39. Cairns BE, Hu JW, Arendt-Nielsen L, et al. Sex-related differences in human pain and rat afferent discharge evoked by injection of glutamate into the masseter muscle. J Neurophysiol. 2001;86:782–791
  40. Ge HY, Madeleine P, Arendt-Nielsen L. Gender differences in pain modulation evoked by repeated injections of glutamate into the human trapezius muscle. Pain. 2005;113:134–140
  41. Jones A, Zachariae R, Arendt-Nielsen L. Dispositional anxiety and the experience of pain: gender-specific effects. Eur J Pain. 2003;7:387–395
  42. Olmarker K, Storkson R, Berge OG. Pathogenesis of sciatic pain: a study of spontaneous behavior in rats exposed to experimental disc herniation. Spine. 2002;27:1312–1317
  43. Takahashi N, Yabuki S, Aoki Y, et al. Pathomechanisms of nerve root injury caused by disc herniation: an experimental study of mechanical compression and chemical irritation. Spine. 2003;28:435–441
  44. Otani K, Arai I, Mao GP, et al. Experimental disc herniation: evaluation of the natural course. Spine. 1997;22:2894–2899
  45. Cihangiroglu M, Yildirim H, Bozgeyik Z, et al. Observer variability based on the strength of MR scanners in the assessment of lumbar degenerative disc disease. Eur J Radiol. 2004;51:202–208
  46. Brant-Zawadzki MN, Jensen MC, Obuchowski N, et al. Interobserver and intraobserver variability in interpretation of lumbar disc abnormalities. A comparison of two nomenclatures. Spine. 1995;20:1257–1263
  47. Milette PC, Fontaine S, Lepanto L, et al. Differentiating lumbar disc protrusions, disc bulges, and discs with normal contour but abnormal signal intensity. Spine. 1999;24:44–53
  48. Pfirrmann CW, Metzdorf A, Zanetti M, et al. Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine. 2001;26:1873–1878
  49. Raininko R, Manninen H, Battie MC, et al. Observer variability in the assessment of disc degeneration on magnetic resonance images of the lumbar and thoracic spine. Spine. 1995;20:1029–1035
  50. vanRijn JC, Klemetso N, Reitsma JB, et al. Observer variation in MRI evaluation of patients suspected of lumbar disk herniation. AJR Am J Roentgenol. 2005;184:299–303

PII: S0161-4754(06)00327-7

doi: 10.1016/j.jmpt.2006.12.004

Journal of Manipulative and Physiological Therapeutics
Volume 30, Issue 2 , Pages 98-108 , February 2007