Advertisement
Original article| Volume 34, ISSUE 4, P231-238, May 2011

Download started.

Ok

Validity of the Straight-Leg Raise Test for Patients With Sciatic Pain With or Without Lumbar Pain Using Magnetic Resonance Imaging Results as a Reference Standard

      Abstract

      Objective

      The aim of this retrospective study was to assess validity of the straight-leg raise (SLR) test using magnetic resonance imaging (MRI) results as a reference standard in a group of patients with L4-L5 and L5-S1 lumbar-herniated disks and sciatic pain. The relationship between diagnostic accuracy of this test, age classes, and grade of lumbar disk displacement was investigated.

      Methods

      The charts of 2352 patients with sciatic pain with/without lumbar pain were examined. Results of the SLR were then compared with previous spinal MRI. A 2 × 2 contingency table was created, and analysis of sensitivity, specificity, positive and negative predictive values, diagnostic odds ratio, likelihood ratio (LR), and receiver operating characteristic (ROC) curve was carried out. Homogeneous age classes were created to compare them statistically.

      Results

      Magnetic resonance imaging findings showed lumbar disk herniation (LDH) in 1305 patients. Of these subjects, 741 were positive on SLR testing. Sensitivity was 0.36, whereas specificity was 0.74. Positive and negative predictive values were 0.69 and 0.52, respectively. Positive LR was 1.38, and negative LR was 0.87. Diagnostic odds ratio was 1.59, and ROC analysis showed an area under the curve (AUC) of 0.596. The AUC decreased from 0.730 in the 16- to 25-year subgroup to 0.515 in the 76- to 85-year subgroup. Similar results were obtained in subjects with LDH and nerve root compression.

      Conclusions

      Our results indicate low accuracy of the SLR in diagnosis of LDH if compared with MRI results. The discriminative power of the SLR seemed to decrease as age increased; thus, positive and negative results may be less conclusive in older patients.

      Key Indexing Terms

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of Manipulative & Physiological Therapeutics
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Devillé W
        • Danielle W
        • Dzaferagic A
        • Bezemer PD
        • Bouter LM
        The Test of Lasègue: systematic review of the accuracy in diagnosing herniated discs.
        Spine. 2000; 25: 1140-1147
        • Airaksinen O
        • Brox J
        • Cedraschi C
        • et al.
        European guidelines for the management of chronic nonspecific low back pain.
        Eur Spine J. 2006; 15: 36-38
        • Lasègue C
        Consideration sur la sciatique.
        Arch Phys Med Rehabil. 1864; 2: 258
        • Vroomen PC
        • de Kram MC
        • Knottnerus JA
        Diagnostic value of history and physical examination in patients suspected of sciatica due to disc herniation: a systematic review.
        J Neurol. 1999; 246: 899-906
        • Rebain R
        • Baxter GD
        • McDonough S
        A systematic review of the passive straight leg raising test as a diagnostic aid for low back pain (1989 to 2000).
        Spine. 2002; 27: E388-E395
        • Rabin A
        • Gerszten P
        • Karausky P
        • Bunker CH
        • Potter DM
        • Welch WC
        The sensitivity of the seated straight-leg raise test compared with the supine straight-leg raise test in patients presenting with magnetic resonance imaging evidence of lumbar nerve root compression.
        Arch Phys Med Rehabil. 2007; 88: 840-843
        • Majlesi J
        • Togay H
        • Unalan H
        • Toprack S
        The sensitivity and specificity of the slump and the straight leg raising tests in patients with lumbar disc herniation.
        J Clin Rheumatol. 2008; 14: 87-91
        • Airaksinen O
        • Brox JI
        • Cedraschi C
        • Hildebrandt J
        • Klaber-Moffett J
        • et al.
        COST B13 Working Group on Guidelines for Chronic Low Back Pain. European guidelines for the management of chronic nonspecific low back pain.
        Eur Spine J. 2006; 15: S192-S300
        • Bossuyt PM
        • Reitsma JB
        • Bruns DE
        • Gatsonis CA
        • Glasziou PP
        • et al.
        Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Standards for Reporting of Diagnostic Accuracy.
        Clin Chem. 2003; 49: 1-6
        • Boos N
        • Rieder R
        • Schade V
        • Spratt KF
        • Semmer N
        • Aebi M
        Volvo Award in clinical sciences. The diagnostic accuracy of magnetic resonance imaging, work perception, and psychosocial factors in identifying symptomatic disc herniations.
        Spine. 1995; 20: 2613-2625
        • Griner PF
        • Mayewski RJ
        • Mushlin AI
        • Groenlandia P
        Selection and interpretation of diagnostic tests and procedures.
        Ann Intern Med. 1981; 94: 555-600
        • Zhou XH
        • Obuchowski NA
        • McClish DK
        Statistical methods in diagnostic medicine.
        Wiley, New York2002
        • Armitage P
        • Berry G
        Statistical methods in medical research. 3rd ed. Blackwell, London1994: 131-148
        • Hanley J
        • McNeil B
        The meaning and use of the area under a receiver operating characteristic (ROC) curve.
        Radiology. 1982; 143: 29-36
        • Swets JA
        Measuring the accuracy of diagnostic systems.
        Science. 1998; 240: 1285-1293
        • DeLong ER
        • DeLong DM
        • Clarke-Pearson DL
        Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach.
        Biometrics. 1988; 44: 837-845
        • Feinstein A.R.
        Principles of medical statistics.
        1st ed. Chapman & Hall/CRC, London2002
        • Inman VT
        • Saunders JB
        The clinico-anatomical aspects of the lumbosacral region.
        Radiology. 1942; 38: 669-678
        • Norman G.
        • Streiner D.
        Biostatistics. The Bare Essentials.
        3rd ed. The McGraw-Hill Education, Berkshire2008
        • Riffenburgh R.
        Statistics in medicine.
        2nd ed. Elsevier Academic Press, San Diego2006
        • Falconer MA
        • McGeorge M
        • Begg AC
        Observations on the cause and mechanism of symptom-reproduction in sciatica and low-back pain.
        J Neurol Neurosurg Psychiatry. 1948; 11: 13-26
        • Holmes D
        • Sworn BR
        Sciatic neuritis.
        BMJ. 1945; 2: 350-351
        • Epstein JA
        • Epstein BS
        • Rosenthal AD
        • Carras R
        • Lavine LS
        Sciatica caused by nerve root entrapment in the lateral recess: the superior facet syndrome.
        J Neurosurg. 1972; 36: 584-589
        • Goddard MD
        • Reid JD
        Movements induced by straight leg raising in the lumbo-sacral roots, nerves and plexus, and in the intrapelvic section of the sciatic nerve.
        J Neurol Neurosurg Psychiatry. 1965; 28: 12
        • Pennybacker J
        Sciatica and the intervertebral disc.
        Lancet. 1940; 238: 771-777
        • Hoyland JA
        • Freemont AJ
        • Jayson MIV
        Intervertebral foramen venous obstruction, a cause of periradicular fibrosis.
        Spine. 1989; 14: 558-568
        • Jayson MI
        The role of vascular damage and fibrosis in the pathogenesis of nerve root damage.
        Clin Orthop Relat Res. 1992; 279: 40-48
        • Edgar MA
        • Park WM
        Induced patterns on passive straight-leg raising in lower limb disc protrusion.
        J Bone Joint Surg Br. 1974; 56: 658-666
        • Kobayashi S
        • Yoshizawa H
        • Hachiya Y
        • Ukai T
        • Morita T
        Vasogenic edema induced by compression injury to the spinal nerve root.
        Spine. 1993; 18: 1410-1424
        • Smith SA
        • Massie JB
        • Chesnut R
        • Garfin SR
        Straight leg raising: anatomical effects on the spinal nerve root without and with fusion.
        Spine. 1993; 18: 992-999
        • Kobayashi S
        • Shizu N
        • Suzuki Y
        • Asai T
        • Yoshizawa H
        Changes in nerve root motion and intraradicular blood flow during an intraoperative straight-leg-raising test.
        Spine. 2003; 28: 1427-1434
        • Thelander U
        • Fagerlund M
        • Friberg S
        • Larsson S
        Straight leg raising test versus radiologic size, shape, and position of lumbar disc hernias.
        Spine. 1992; 7: 395-399
        • Brisby H
        • Olmarker K
        • Larsson K
        • Nutu M
        • Rydevik B
        Proinflammatory cytokines in cerebrospinal fluid and serum in patients with disc herniation and sciatica.
        Eur Spine J. 2002; 11: 62-66
        • Borenstein DG
        • O'Mara JW
        • Boden SD
        • et al.
        The value of magnetic resonance imaging of the lumbar spine to predict low-back pain in asymptomatic subjects: a seven-year follow-up study.
        J Bone Joint Surg. 2001; 83-A: 1306-1311
        • Grönblad M
        • Virri J
        • Seitsalo S
        • Karaharju E
        Inflammatory cells, motor weakness, and straight leg raising in transligamentous disc herniations.
        Spine. 2000; 25: 2803-2807
        • Walsh J
        • Hall T
        Agreement and correlation between the straight leg raise and slump tests in subjects with leg pain.
        J Manipulative Physiol Ther. 2009; 32: 184-192